August was another big month for startup funding, and the most active investor rankings were once again dominated by familiar names.

Always-busy Y Combinator was the most active backer of U.S.-based startups by deal count, while General Catalyst led or co-led the most rounds of $5 million or more, Crunchbase data shows.

Chip giant Nvidia, meanwhile, sharply accelerated its dealmaking, ranking among the most active and highest-spending investors for the month. The chip giant participated in nine disclosed rounds of at least $5 million — marking its busiest month for investing since at least the beginning of 2025 — and led or co-led financings collectively valued at $1.3 billion.

The flurry of activity came as global venture funding reached $42 billion in August, up 122% year over year, with seven companies raising billion-dollar-plus rounds last month.

Below, we rank August’s most active startup investors across several categories, including lead backers, prolific venture dealmakers, highest spenders and seed investors.

Active lead investors

San Francisco-based General Catalyst ranked as the most active lead investor in rounds of $5 million or more, leading or co-leading five such deals. Its largest was the $1.1 billion Series A for River AI, which provides custom AI fine-tuning for businesses. General Catalyst also led or co-led a $116 million Series E for Cityblock Health, along with three seed rounds ranging from $10 million to $25 million, Crunchbase data shows.

Andreessen Horowitz, Sequoia Capital and S3 Ventures tied for second, with four lead or co-lead deals each.

The scale of those rounds varied considerably. The four deals that Andreessen led or co-led totaled more than $1.15 billion, driven by an $800 million Series C for defense tech company Castelion and a $300 million Series A for AI infrastructure startup Volta.

Sequoia’s four led or co-led deals totaled $1.3 billion, including a $1 billion Series B for nuclear energy startup Valar Atomics.

Busiest venture investors

When we widen the ranking to include both lead and non-lead participation in rounds of $5 million or more, Y Combinator once again takes the top spot.

The accelerator participated in at least 18 such deals in August, per Crunchbase data. As we’ve noted in previous rankings, Y Combinator commonly invests as a non-lead backer in follow-on rounds for companies that previously went through its program.

Andreessen Horowitz ranked second with 13 deals, followed by General Catalyst with 10. Alumni Ventures and Nvidia tied for fourth with nine each.

Nvidia’s rise in the investor rankings is particularly notable. The Santa Clara, California-based chip giant participated in only four U.S. rounds of $5 million or more in July and one in August 2025. Seven of its nine qualifying investments last month went to companies categorized as AI-focused in Crunchbase, including River AI, Poolside, Groq, Starcloud and Generalist AI.

The August burst extends a notable increase in Nvidia’s venture dealmaking pace this year. Crunchbase data shows that by mid-August, it had participated in a record 59 known startup funding rounds in 2026, already surpassing its 53 investments in all of 2025. It had also led or co-led at least 11 private-company financings this year, underscoring its growing role as both a technology supplier to and financial backer of the AI startup ecosystem.

RA Capital Management and Sequoia were next in our August rankings, each with seven U.S. startup investments of $5 million or more. RA Capital’s portfolio reflected its life sciences focus, with August deals including LifeMine Therapeutics, AusperBio, Expedition Therapeutics, Infinimmune and Abcuro.

Highest-spending investors

The rankings change again when we look at lead investors associated with the highest aggregate deal values.

For August, Coatue was the apparent spendiest lead investor, thanks to its role leading Databricks’ $5 billion deal. The round, the month’s largest, valued the data and AI company at $190 billion.

JPMorganChase and Valor Equity Partners followed, each leading or co-leading rounds with an aggregate value of $2.37 billion, as both were listed as lead investors in defense manufacturing startup Hadrian’s $1.37 billion Series D and home battery provider Base Power’s $1 billion Series D.

Nvidia and Sequoia came next, each with $1.3 billion in led or co-led rounds. Nvidia’s total came from Poolside’s $1 billion financing and Volta’s $300 million Series A, while Sequoia led or co-led four rounds, topped by the Valar Atomics financing.

General Catalyst and Andreessen also crossed the $1 billion mark, with approximately $1.26 billion and $1.15 billion, respectively, in aggregate led round value.

As always, this is an approximation of spending rather than a tally of capital actually contributed. Investors rarely disclose how much each participant put into a round, although lead investors generally contribute a substantial share.

Seed dealmakers

At seed, Y Combinator was again the most prolific investor, backing at least 12 U.S.-headquartered companies in August.

Orbital Edge Accelerator ranked second with eight seed investments, all announced as part of the same August cohort. NMotion and Techstars followed with six seed deals each, while SV Angel 1 recorded five. (It’s important to note that seed rankings are especially subject to change, since smaller financings often take longer to be reported and added to the Crunchbase dataset.)

Big checks, familiar names

August’s rankings tell a now-familiar story: A relatively small group of large venture firms continues to dominate by deal count, while a handful of megadeals determines who tops the spending ranks. But Nvidia’s acceleration this year also illustrates how corporate investors — particularly those with a direct stake in the AI ecosystem — are becoming increasingly prominent alongside traditional venture firms.

Related reading:

• Global Venture Funding Jumps 122% In August As Streak Of Billion-Dollar Deals Continues
• No Summer Doldrums For Active Startup Investors In July

Methodology

This analysis covers reported investments in U.S.-headquartered companies and is based on Crunchbase data pulled Sept. 10, 2026. Rankings for active venture and lead investors include rounds of $5 million or more. Seed rankings include angel, pre-seed, seed and equity crowdfunding rounds.

Funding data is subject to reporting lags, which are typically most pronounced at the seed stage.

Illustration: Dom Guzman